Cardiac reentry modeled by spatiotemporal chaos in a coupled map lattice

Arrhythmias are potentially fatal disruptions to the normal heart rhythm, but their underlying dynamics is still poorly understood. Theoretical modeling an important tool fill this gap. Typical studies often employ detailed multidimensional conductance-based models. We describe cardiac muscle with a three-dimensional map-based membrane potential model in lattices. Although maps retain biophysical behavior of cells and generate computationally efficient tissue models, few have used them understand dynamics. Our study captures healthy pathological behaviors fewer parameters simpler equations than conductance successfully generalize results obtained previously reaction–diffusion systems, showing how chaotic properties result reentry, propagation stimuli that evolves arrhythmias complex spatiotemporal features. The bifurcation diagram single cell very similar model. find torsade de pointes, clinical manifestation some types tachycardia electrocardiogram, using generic sampling whole network during spiral waves. also novel type dynamical pattern, wavefronts composed synchronized plateaus bursts. provides first in-depth look at use models simulate